Friday, April 20, 2007

Bank your Body


Freezing your physical assets - from skin to eggs - is a controversial new trend in anti-ageing. So will you invest? CLAIRE COLEMAN investigates more:

Remember a few years ago when your skin was clearer, your body was thinner and you could run up five flights of stairs without breaking into a sweat?

And now imagine how seductive it would be if someone offered you the chance to freeze time, halt the ageing process and always look and feel as great as you did at the age of 21.

Until recently, the possibility of doing anything remotely resembling this would have been considered science fiction.

Now advances in medical technology mean that increasing numbers of us can, to a certain extent, if not stop time, at least freeze our assets at the point at which they are most valuable so that we can return to them when we need, literally, an injection of youth and vigour in the future.

Banking your body is the latest trend in anti-ageing and with the huge advances being made in cell collection, storage and replication, it looks set to grow and grow over the next decade. And the implications, for everything from our skin and our hair, to our fertility, are staggering.

COLLAGEN
As we age, the quantity and quality of collagen in our skin degenerates, resulting in skin that is less toned and prone to wrinkles. Injecting new collagen can counteract these problems and, while collagen can be obtained from various sources - including cows, pigs and even dead bodies - many people prefer the thought of autologous collagen (reinjection of one's own collagen).

in the USA some will separate it from other tissues after one type of operation (liposuction/breast reduction) and store it for use in the patient's face in the future. Dr Thierry Vidal of London's Skin Health Spa thinks that such procedures will be commonplace in the future.

there's no doubt that in the future it could be quite common for young people to store samples of collagen and other tissues that degrade with age, with a view to using them in an anti-ageing process in later life.'

SKIN

Maintaining baby soft skin forever might be a real possibility in the future. A product currently available called ReCell or CellSpray uses a sample of the patient's own skin to create a sprayable skin solution that contains all the skin cells necessary for healthy skin growth and can then be applied to a wound or damaged area of skin.

The company is also able to replicate the skin cells in a lab, should more cells be required. At the moment the technology is predominantly used on burns patients but, according to Matthieu Leclerc-Chalvet of Clinical Cell Culture, the company behind ReCell:

'The cosmetic applications for this treatment can be combined with something like laser resurfacing or dermabrasion to reduce the risks of scarring and improve healing.'

FAT

Although fat has its drawbacks as a filler for wrinkles (it tends to be reabsorbed by the body and so needs regular top ups), fat transfer, where fat is removed from one area of the body and then re-injected into another part, is a relatively commonplace procedure.

One significant advantage is that the body's own fat cells are less likely to cause an allergic reaction or be rejected by the body than a synthetic or foreign substance. In most instances, surgeons will remove and re-inject the fat at the same time.

However it is possible to freeze fat so that a patient can have top-ups of their own cells over a longer period of time, a popular practice in the US.

Danya Hoenig, a medical assistant who works with her husband, Los Angeles plastic surgeon Jonathan Hoenig explains, 'We have a clinical-grade freezer here which stores fat at minus 30 degrees Fahrenheit.

We will keep fat samples for around a year, defrosting small amounts at a time so it can be used for cheek augmentation and similar facial procedures.'

VEINS

The idea of taking out parts of your body that you don't want and then recycling them in ways that you do has a certain satisfying symmetry about it. And fat is not the only substance to be used in this way.

It has been reported that some cosmetic surgeons in the US are storing varicose vein tissue, that has been removed from a patient's legs, and subsequently using the collagen it contains to inject it into their face as a filler.

HAIR

Help may be at hand for those concerned about hairloss, or hair that thins with age. While hair transplants are relatively common procedures at the moment, where hair follicles are removed from one part of the scalp and reimplanted in another area, new technologies which allow scientists to replicate hair follicles in the lab could mean that, in theory, young healthy hair follicles could be removed from a small, inconspicuous area at the nape of the neck, multiplied in the laboratory and then stored to be reimplanted at strategic locations, either to thicken existing hair or where baldness has set in.

'While it's not happening at the moment, storing hair follicles in case you suffer from hair loss in later life could certainly be a possibility in the future," says Consultant Plastic Surgeon Jim Frame, of the Capio Springfield Hospital in Chelmsford, Essex.

He also believes this sort of hair grafting could also come in handy when performing facelifts. 'In a lot of cases, when a facelift is performed, the hairline moves and this can look unnatural,' explains Mr Frame. 'Reimplanting hair follicles to recreate a more natural hairline could be a solution to this.'

EGGS

In a society where we're increasingly having children later in life, be it due to careers or simply not finding the right man, the prospect of putting healthy, young eggs on ice is very attractive.

But while sperm banking is nothing new, egg freezing is much more complicated, less effective and, therefore, less common. However, new technologies are currently being worked on that could change all that within 12 months.

Dr Fishel estimates that while the majority of egg freezing cases Care Fertility sees are women who wish to freeze eggs for medical reasons (such as before having cancer treatment), around one in three cases are for lifestyle reasons.

And he believes that as the new techniques are introduced this trend will become more commonplace.

'If I had a daughter in her mid-20s who was on a career path and not considering conception until her mid to late 30s, I would certainly suggest that she went through a couple of cycles of egg stimulation with a view to freezing around 30 healthy eggs.'

Dr Fishel says he would not be surprised if egg freezing became routine.

'When you think about the cost of endless cycles of IVF for older women, plus the elevated risks of Down's Syndrome when using older eggs, in a society where women are increasingly having children later, freezing eggs is, frankly, a sensible thing to do.'

BODY PARTS

One of the other alternatives to egg freezing is a technique called ovarian cryopreservation where, pre-treatment cancer patients have slivers of their ovaries removed and frozen, and then subsequently reimplanted after treatment and, once transplanted, begin to release eggs and work in the same way as undamaged ovaries.

This is a procedure that Kylie Minogue underwent prior to her cancer treatment. But a company called Alcor in the US lets you go one step further and freeze your entire body. Believers in cryogenics are convinced that, one day in the future, the technology will be available to bring them back to life once more.

To be accurate, the process Alcor uses is not freezing, but vitrification, where more than 60 per cent of the water in the body's cells is replaced with protective chemicals which means that rather than actually freezing and forming ice crystals which can destroy body tissues, it is just deep cooled and then suspended in a tank of liquid nitrogen.

STEM CELLS

Stem cell banking hit the news recently as Richard Branson announced the latest Virgin venture, Virgin Health Bank, a company that offers new parents the opportunity to preserve cells from the blood of their newborn child's umbilical cord. Stem cells are the cells from which all other cells form - everything from the teeth and skin to bone and the heart.

Although the research is still in its infancy, many in the industry believe that stem cells are the future of medicine. 'Stem cells literally have the ability to turn back time,' says medical scientist, Dr Cuross Bakhtiar of London's Harley Street Cosmetic.

'They have the potential to regenerate blood cells damaged by heart attacks and even improve sight damaged by retinal degradation.'

Dr Donald Gibb, an obstetrician in private practise in London's Harley Street, has seen the number of parents looking to bank stem cells increase over the past few years.

'For several years now I've made my patients aware of the possibility of banking stem cells when their child is born and I would say roughly 20 per cent of them do so.' He believes this number could well increase further.

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